mGFR Resources

In kidney disease, Glomerular Filtration Rate (GFR) is the primary indicator of injury, disease progression, and recovery. Currently, Serum Creatinine (SCr) is the most common clinical assay for estimating renal function (eGFR). This is a poor surrogate for true GFR as it is a trailing indicator by approximately 24-48 hours. Patients lose approximately 50% of their kidney function by the time the serum creatinine measures above normal. It is slow to reflect kidney impairment and recovery and is impacted by non-renal factors of age, diet, muscle mass, and hemodynamics.

Article Title Journal Name

A Novel Method for Rapid Bedside Measurement of GFR

American Society of Nephrology

An Overview of Errors and Flaws of Estimated GFR versus True GFR in Patients with Diabetes Mellitus

Nephron: Clinical Practice

Measured GFR as a Confirmatory Test for Estimated GFR

American Society of Nephrology

Rethinking CKD Evaluation: Should We Be Quantifying Basal or Stimulated GFR to Maximize Precision and Sensitivity?

American Journal of Kidney Diseases

Assessment of Iothalamate Plasma Clearance: Duration of Study Affects Quality of GFR

American Society of Nephrology

A portable Fiberoptic Ratiometric Fluorescence Analyzer Provides Rapid Point-of-Care Determination of Glomerular Filtration Rate in Large Animals

International Society of Nephrology

A Comparison of Prediction Equations for Estimating Glomerular Filtration Rate in Adults without Kidney Disease

American Society of Nephrology