mGFR Resources

In kidney disease, Glomerular Filtration Rate (GFR) is the primary indicator of injury, disease progression, and recovery. Currently, Serum Creatinine (SCr) is the most common clinical assay for estimating renal function (eGFR). This is a poor surrogate for true GFR as it is a trailing indicator by approximately 24-48 hours. Patients lose approximately 50% of their kidney function by the time the serum creatinine measures above normal. It is slow to reflect kidney impairment and recovery and is impacted by non-renal factors of age, diet, muscle mass, and hemodynamics.

Article Title Journal Name PDF
Assessment of Iothalamate Plasma Clearance: Duration of Study Affects Quality of GFR American Society of Nephrology Download PDF
A portable Fiberoptic Ratiometric Fluorescence Analyzer Provides Rapid Point-of-Care Determination of Glomerular Filtration Rate in Large Animals International Society of Nephrology Download PDF
A Comparison of Prediction Equations for Estimating Glomerular Filtration Rate in Adults without Kidney Disease American Society of Nephrology Download PDF