Volume Status (Plasma Volume)

Knowing volume status is key in critical care. The American College of Cardiology and American Heart Association recommend assessing volume status in all heart failure patients. Even small 10% increases in volume are directly linked to worse outcomes and longer hospital stays.

A third of all ICU patients has an episode of volume resuscitation, and a quarter of all ICU patients suffer from acute kidney injury (AKI).

Current surrogates include:

  • Swan Ganz catheter
  • ECHO
  • CVP
  • Clinical observation

These methods are either invasive, inconsistent or only catch the extremes. They are often measures of cardiac function rather than quantifications of actual fluid volume. One FDA approved product to measure blood volume has limited clinical viability due to cumbersomeness and use of a radioactive isotope. Often, physicians are estimating volume status using a combination of methods and clinical observation.

I don’t think any of them are great. Not one of them is good enough alone and we sometimes miss.

- Cardiac Surgeon on current methods being used for determining volume status

If I knew precisely what my patient’s circulating blood and/or volume status was, it would change the way I practice medicine in the ICU, particularly in situations where it is hard to estimate, for example in cardiac surgery and sepsis patients

- Anesthesiologist in regards to the impact of FAST BioMedical’s technology.