Two key metrics are required to determine optimal therapy for fluid overload:
No clinical viable options for accurate measurement of intravascular volume exist in current practice.
The frontline treatment for Congestive Heart Failure is fluid removal using diuretic therapies. It is difficult to determine the appropriate dose leading to too much or too little fluid removal.
The challenge – to correctly dose diuretics to manage a patient’s volume status and kidney function when you cannot accurately and readily measure these parameters.
- Costanzo, MR et al.1
- American Heart Association
1Costanzo, MR et al. Ultrafiltration Versus Intravenous Diuretics for Patients Hospitalized for Acute Decompensated Heart Failure. JACC 2007;40:675-683